An apocryphal tale that Stan Lee passes along is that Spider-man's success could be attributed as much to the standard superhero trappings as the personal struggles that everyone has dealt with, citing Peter Parker's acne as an example. but can you cite an actual example. Issue number, story, anything? The closest I can come up with is after Peter kisses Mary Jane and she wonders if he's blushing or if it's acne. Anyway, if you're more worried about your skin than comic book trivia you might look into what's called the best acne treatment. And as with all medical matters, consult with a physician before undergoing any treatment regimen.